GENETIC TOXICITY

Genotoxicity is the study of the effect of chemicals on nucleic acid stability. The branch of genetic toxicology has evolved in response to the concern that certain chemicals have been found to induce mutations in various experimental systems. These chemicals are likely to affect the incidence of heritable disease in man and/or be potentially carcinogenic. Various tests based on diversified mutagenic effects have been recommended by The Organization for Economic Co-operation and Development (OECD) for evaluation of mutagenic potential of the test chemicals.

 

RRL has vast expertise and experience in genotoxicity. We have a well-organized, purpose-built facility to conduct all the standard in vitro genetic toxicology assays. Each assay uses protocols that comply with harmonized international guidelines.

GENOTOXICITY STUDIES

  • Ames

  • In vitro Gene mutation

  • In vitro Micronucleus

  • In vitro Chromosomal aberration

  • In vitro Skin Irritation

  • In vitro Skin Corrosion

  • In vitro Eye Irritation

  • In vitro Eye Corrosion

  • In vitro Skin Sensitization

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